Ozempic has been linked to yet one more unintended aspect impact: hair loss.
DailyMail.com first reported on Ozempic inflicting hair loss in early 2023, after customers posted movies on-line of clumps of hair falling out into the sink.
Now, a brand new examine has backed up these anecdotes.
Scientists tracked almost 3,000 Individuals who used both semaglutide, the lively drug in Ozempic and Wegovy, or older weight reduction drug bupropion-naltrexone, or Contrave.
General, semaglutide customers had been discovered to be 52 % extra prone to lose their hair whereas on the drug in comparison with those that took the opposite weight reduction drug.
And amongst ladies, the chance of hair loss in semaglutide customers was double that within the different group.
The general dangers had been nonetheless fairly low, with round 1 % of sufferers reporting hair loss.
Researchers recommended the drug could cause hair to fall out due to the fast weight reduction the drug triggers — at as much as 2lbs every week.
They mentioned this places the physique beneath monumental stress and might disrupt hair’s pure progress cycle, inflicting many hairs to fall out without delay.
An American girl on Mounjaro mentioned on her TikTok her hair was falling out in clumps when she brushed it or showered
It is not clear what number of Ozempic customers are at the moment affected by hair loss.
Different weight reduction medication, corresponding to tirzepatide — offered beneath the model identify Mounjaro — which trigger fast weight reduction have additionally been linked to the aspect impact.
The knowledge leaflets for Wegovy and Ozempic lists hair loss as a potential aspect impact.
In the newest examine, which was revealed as a pre-print on-line and has not been peer-reviewed, scientists analyzed knowledge on 16million Individuals from the US-based healthcare claims database IQVIA PharMetrics Plus for Teachers.
Knowledge from 2006 to 2020 was reviewed to search out sufferers who used both semaglutide or Contrave particularly for weight reduction.
Sufferers who had diabetes or used medicines to decrease their blood sugar had been excluded from the evaluation.
Bupropion-naltrexone is a weight reduction drug that works on the mind to scale back cravings for meals, and was first accepted by the FDA to be used in 2014.
It’s given as a pill, relatively than an injection, and in trials led sufferers to lose about 10 % of their body-weight in a 12 months.
For comparability, semaglutide, which is accepted for diabetes, can set off the lack of 10 % of somebody’s body-weight in six months.
The examine included 1,926 semaglutide sufferers, of which 23 — or 1.1 % — reported affected by hair loss.
Sufferers on this group had been 55 years previous on common, whereas 53 % had been feminine and 5 % had been concurrently taking steroids — which may additionally trigger hair loss.
Sufferers on this group had been additionally extra prone to be depressed and to have hypothyroidism, an over-active thyroid, which may each increase the chance of hair falling out.
Some experiences have recommended taking semaglutide could increase the chance of despair, however a serious examine revealed final month recommended that the drug may truly enhance folks’s psychological well being. And Research don’t recommend semaglutide raises the chance of thyroid issues.
For comparability, within the Contrave group there have been 1,348 sufferers, together with 27 — or two % — who reported affected by hair loss.
These people had been 46 years previous on common, whereas 80 % had been feminine, and 6 % had been utilizing steroids.
After adjusting for components together with age, intercourse, location and steroid use, the researchers discovered these on semaglutide had been 52 % extra prone to endure from hair loss.
The examine was carried out on sufferers who used semaglutide, the drug in Ozempic, and people who used an older class of weight reduction medication
Scientists additionally recommend semaglutide could trigger hair loss as a result of it may result in a scarcity of vitamins within the physique. This could possibly be attributable to consuming much less and in addition by side-effects corresponding to vomiting.
The scientists, from the College of British Columbia, mentioned within the examine: ‘Our outcomes reveal an elevated threat of hair loss with semaglutide in ladies.
‘Future research are required to establish the affiliation between semaglutide and hair loss.’
This is not the one unintended aspect impact of Ozempic, with others together with nausea, diarrhea and abdomen ache.
About 13 % of US adults have tried semaglutide at the very least as soon as, surveys recommend, after it was popularized by Hollywood celebrities for its promise to assist somebody quickly drop a few pounds with little greater than a weekly injection.
Novo Nordisk, the maker of Ozempic, mentioned in an announcement that it ‘stays assured within the benefit-risk profile of our GLP-1 medicines, when used according to their indications and product labeling.’
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